The Centre de Recerca en Sanitat Animal (CReSA) was initially a public foundation focused on research, technological development, studies and education in the sphere of animal health, in collaboration with other academic and research institutions, and the private sector. Created in 1999 by initiative of the Universitat Autònoma de Barcelona (UAB) and Institut de Recerca i Tecnologia (IRTA), was fully integrated in IRTA at January 2015. The CReSA unites the human potential for research in animal health of both founding institutions, and takes advantage of a new technologically advanced building, with level-3 biocontainment (BSL3). The CReSA works to improve animal health and the quality and safety of animal products destined for human consumption. The researchers carry out research into innovative and effective vaccines; they study epidemiology, immune response and pathogenic mechanisms, assess risks for human health and develop standardized models of infection and diagnostic techniques. Besides matters of scientific interest, the studies carried out at the CReSA have different implications for consumers, producers and regulatory institutions. CReSA, from the very beginning was broadly opened to contract with animal health related private companies. The CReSA also conducts actions for the Government of Catalonia. Commissioned by the Department of Agriculture, Food and Rural Action, the Centre has established plans for the monitoring and control of different diseases. It also collaborates with the Department of Health in the diagnosis of spongiform diseases, in the training and assessment of slaughterhouse vets and also in the virological arthropod vector surveillance.