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Real-time impedance measurement based cell adhesion and migration / invasion co-measuring equipment (GCI-SU)
Identification
Hosting Legal Entity
Semmelweis University
Location
Nagyvárad tér 4, Budapest, PO: 1089 (Hungary)
Structure
Type Of RI
Single-sited
Coordinating Country
Hungary
Status
Status
Current Status:
Operational since 2008
Scientific Description
The research infrastructure provides the possibility of a real-time measurement of cell adhesion and migration. The complex set-up of the infrastructure represents the highest degree of capabilities among the available platforms not only in Hungary but also in Europe, and offers the measurement of: (i) the kinetics of cell adhesion; (ii) the micro-motion of the adherent cells; (iii) the proliferation and responses to cytotoxic drugs. Wound healing assay methodology is also available to characterize, i.e., invasive tumor cells.

RI Keywords
Chemotaxis, Wound-healing, Electroporation, Motion analysis, Cell adhesion, Migration
Classifications
RI Category
Clinical Research Centres
Cell Culture Facilities
Biomedical Imaging Facilities
Scientific Domain
Biological and Medical Sciences
ESFRI Domain
Health and Food
Services
Data Analysis
Training
Real-Time Measurement of Cell Adhesion and Migration
Experimental Design
Equipment
Inverted Microscope

Zeiss AXIO Observer A1, furnished with module for tracking of moving objects in 2D time lapse images.

Cell Counter and Analyzer System

CASY TT System.

Electric Cell-Substrate Impedance Sensor

ECIS-1600, ECIS-Theta Z.

xCELLigence SP System

Biological parameters screened: cell adhesion, proliferation/cytotoxicity, barrier function; HTS technology: 96 wells (E-plate).

Date of last update: 09/05/2017
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