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National Institute for Cellular Biotechnology Core Facilities (NICB)
Identification
Hosting Legal Entity
Dublin City University
Location
Collins Avenue, National Institute for Cellular BiotechnologyDublin City University, Dublin, PO: 9 (Ireland)
Structure
Type Of RI
Single-sited
Coordinating Country
Ireland
Status
Status
Current Status:
Operational since 2006
Scientific Description
The NICB is a multidisciplinary centre of research in fundamental and applied Cellular Biotechnology, Molecular Cell Biology, Ocular diseases and Biological Chemistry. It includes a multidisciplinary team of Cell and Molecular Biologists, Biotechnologists. Chemists and Computer Scientists. The institute draws from the established expertise of researchers in Dublin City University, IT Tallaght and NUI Maynooth with the aim to be a Centre of world-class expertise, in Cellular and Molecular Biotechnology, a diverse and expanding interdisciplinary science. The NICB has combined the variety of expertise of its researchers to develop targeted research programmes in key areas relating to identification of new therapeutic targets and diagnostic methods for disease (in particular for cancer, microbial diseases and diabetes) and understanding of basic biological processes including regulation of gene expression during cell differentiation and their translational to industrial and medical applications.

RI Keywords
Bioinformatics, Biotechnology, MicroRNA, Tissue engineering, Diabetes, Biopharmaceutical production, Oncology, Chemical synthesis, Stem cell biology, Pharmacokinetics, Medicine, Toxicology, Functional genomics, Proteomics, Transcriptomics, Biological chemistry, Molecular biology, Ocular disease
Classifications
RI Category
Complex Data Facilities
Bio-informatics Facilities
Translational Research Centres
Clinical Research Centres
Systems Biology/Computational Biology Facilities
Collections of Biological Resources (e.g. Microorganisms, Biobanks and Seed Banks)
Data Mining and Analysis (Methodological) Centers, including statistical analysis
Cell Culture Facilities
Analytical Facilities
Genomic, Transcriptomic, Proteomics and Metabolomics Facilities
Scientific Domain
Chemistry and Material Sciences
Biological and Medical Sciences
ESFRI Domain
Health and Food
Equipment
Proteomics Software

Decyder 6.5 (GE Healthcare) Progenesis SameSpots (NonLinear Dynamics) Protein Pilot (Applied Biosystems) MASCOT (Matrix Science) SEQUEST/Bioworks (Thermo Fisher Scientific) PEAKS - de novo sequencing.

GCS3000 7G Upgrade

For scanning ST arrays.

Workstation FSCDDC1

For running array hardware and software.

GCS3000 7G Scanner & Autoloader

For automated scanning of microarray chips.

qPCR

Applied Biosystems 7600.

Flow Cytometry/ Cell sorting

Guava EasyCyteBD FACSAria.

Hybridisation Oven 640

For hybridisation of samples to microarray chips.

Leica SP2 AOBS Confocal Microscope

Optical sectioning of samples with greater resolution compared to standard epi-fluorescence imaging. The system is capable of spectral scanning and unmixing and is suitable for FRAP, FLIP and FRET.

FS-450 Fluidics station

For washing and staining microarray chips.

Proteomic sample preparation

Ettan Spot Picker robot (GE Healthcare)Ettan Spot Digestor robot (GE Healthcare)Ettan Spotter robot (GE Healthcare).

Typhoon 9400

Fluorescent scanner (GE Healthcare).

Liquid chromatography

Ultimate 3000 LC system (Dionex).

Advanced mass spectrometry equipment for proteomics

4800 Plus MALDI TOF TOF (Applied Biosystems) LTQ-Orbitrap XL (Thermo Fisher Scientific) LTQ XL with ETD (Thermo Fisher Scientific).

IPGphor (GE Healthcare)

Electrophoresis unit.

Date of last update: 31/01/2018
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