ISIS provides neutron and muon beams used to study the structure and dynamics of materials at the atomic and molecular level. The suite of over 30 neutron and muon instruments enables pure and applied science across a broad range of scientific fields, from physics and chemistry, through biological and material sciences to earth sciences, pharmacology and engineering. Neutrons are produced from two target stations, the second of which started operations in 2008 and is optimised for advanced materials, soft matter and bioscience studies. ISIS is unique in Europe as a pulsed source of neutrons and muons. It is open to university and industrial researchers from the UK, Europe and beyond, and has a variety of access mechanisms including one specifically for industrial users.