NCT is a comprehensive cancer center uniquely positioned to benefit from the wealth of DKFZ cancer research and the Heidelberg biomedical campus. Established in 1964, the German Cancer Research Center (DKFZ) is the largest biomedical research center in Germany and one of Europe’s leading oncologic research institutions. In over 100 divisions and research groups (with 24 junior groups), a staff of approximately 3000 members including more than 1,000 scientists have undertaken the mission to unravel the causes and mechanisms underlying cancer development and progression and, based on innovative research, to develop novel strategies for the diagnosis, early detection, prevention, and treatment of cancer. DKFZ has a track record in outstanding biomedical research with translational platforms consolidated into NCT. DKFZ’s many disciplines and interactions, strategic partnerships with academia and industry, provide a strong framework for NCT projects. DKFZ gives NCT full access to its excellent research infrastructure. Heidelberg University Medical Center is one of the largest and most prestigious medical centers in Europe (staff: 6000), with approximately 800,000 patient visits annually. In more than 40 clinics, 59,700 inpatients are seen every year, and 40% of these contacts are cancer-related. Modern premises, state-of-the-art equipment and efficient workflows enable high-performance medicine. Heidelberg University Medical Center has integrated all clinical departments with oncological activities into NCT. NCT serves as the common entry portal for all oncology outpatients on the Heidelberg Medical Campus. NCT’s mission is two-fold: to provide optimal interdisciplinary oncology with current clinical therapies and to rapidly transfer scientific knowledge into clinical applications through comprehensive translational and preventive oncology.