The Molecular Small Animal Imaging Center (MoSAIC) is a core facility of the University of Leuven (KU Leuven). It combines all major in vivo imaging modalities for pre-clinical research (Magnetic Resonance, Positron Emission Tomography, Ultrasound, optical imaging (bioluminescence, fluorescence, intravital microscopy, OCT) and computed tomography). Supporting infrastructure is available in the biosafety laboratory space. Close links to the Department of Imaging and Pathology exist that allow rapid translation of pre-clinical findings. Research is performed in all field of biomedical sciences (for example neurology, cardiology, oncology, infectious diseases, endocrinology etc.). The core facility MoSAIC is also linked to the Medical Imaging Research Center (MIRC) at KULeuven, which is a collaborative project of the faculties of Medicine and Engineering focussing on image processing. The molecular imaging program includes research on the development of novel tracers, contrast agents and imaging reporters.The interdisciplinary team for this project consists of 9 professors (3 radiology/biomedical MRI, 2 Nuclear Medicine, 1 Endocrinology, 1 radiation therapy, 1 MIRC, 1 radiopharmacy), 2 post-docs/research experts MoSAIC, 7 PhD students and 2 technicians (core facility MoSAIC).