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Proteomics French Infrastructure (ProFI)
Identification
Hosting Legal Entity
French National Institute of Health and Medical Research (INSERM)
Address:
16 avenue Paul Vaillant Couturier, Villejuif (France)
French Alternative Energies and Atomic Energy Commission
Address:
Gif-sur-yvette cedex, PO: 91191 (Undefined)
French National Center for Scientific Research / Centre National de la Recherche Scientifique (CNRS)
Address:
3 Michel-Ange street, CNRS, Paris, PO: 75794, Ile-de-France (France)
Location
France
Structure
Type Of RI
Distributed
Coordinating Country
France
Status
Status
Current Status:
Operational since 2015
Scientific Description
Proteomics aims to characterize proteomes in-depth with a view to functional proteomics and clinical applications. This leads to new challenges, including how to determine variations within the proteome as a result of various stimuli or different cellular states, detect low abundance proteins important for biology or health, study the dynamics of protein complexes, analyze post-translational modifications playing a key role in protein function. In this highly challenging context, France has created the Proteomics French Infrastructure (ProFI) in 2012 for a 7 years funding (15 M€). It is a shared infrastructure which groups together the three most renowned French proteomics platforms: the “Exploring the Dynamics of Proteomes” Laboratory (CEA, INSERM and Grenoble Alpes University), the “Laboratoire de Spectrométrie de Masse Bio-Organique” (CNRS and Strasbourg University) and the “Proteomics and Mass Spectrometry of Biomolecules” research group (CNRS and Toulouse Paul Sabatier University). The objectives of ProFI are twofold: (1) R&D activities in quantitative proteomics and in bioinformatics; (2) make the services offered by ProFI widely available to the scientific community and industrial actors by setting up a highly technical environment compatible with the production and treatment of high quality data at very high throughput and in a context of quality assurance certification.

RI Keywords
Systems biology, Plant biology, Technology survey & development, Mass spectrometry, High performance IT & bioinformatics, Oncology, Service to the community, Cell biology, Immunology, Microbiology
Classifications
RI Category
Genomic, Transcriptomic, Proteomics and Metabolomics Facilities
Scientific Domain
Information Science and Technology
Biological and Medical Sciences
Services
Proteomics

Shotgun proteomics; Targeted proteomics; Identification of post-translational modifications.

Equipment
Mass spectrometry systems

Orbitrap and Q-Trap instruments.

Collaborations
Networks
PRIME-XS
Date of last update: 24/05/2018
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