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Proteomics French Infrastructure (ProFI)
Identification
Hosting Legal Entity
French Alternative Energies and Atomic Energy Commission
Address:
Gif-sur-yvette cedex, PO: 91191 (Undefined)
French National Center for Scientific Research / Centre National de la Recherche Scientifique (CNRS)
Address:
3 Michel-Ange street, CNRS, Paris, PO: 75794, Ile-de-France (France)
French National Institute of Health and Medical Research (INSERM)
Address:
16 avenue Paul Vaillant Couturier, Villejuif (France)
Location
France
Structure
Type Of RI
Distributed
Coordinating Country
France
Status
Status
Current Status:
Operational since 2015
Scientific Description
Proteomics aims to characterize proteomes in-depth with a view to functional proteomics and clinical applications. This leads to new challenges, including how to determine variations within the proteome as a result of various stimuli or different cellular states, detect low abundance proteins important for biology or health, study the dynamics of protein complexes, analyze post-translational modifications playing a key role in protein function. In this highly challenging context, France has created the Proteomics French Infrastructure (ProFI) in 2012 for a 7 years funding (15 M€). It is a shared infrastructure which groups together the three most renowned French proteomics platforms: the “Exploring the Dynamics of Proteomes” Laboratory (CEA, INSERM and Grenoble Alpes University), the “Laboratoire de Spectrométrie de Masse Bio-Organique” (CNRS and Strasbourg University) and the “Proteomics and Mass Spectrometry of Biomolecules” research group (CNRS and Toulouse Paul Sabatier University). The objectives of ProFI are twofold: (1) R&D activities in quantitative proteomics and in bioinformatics; (2) make the services offered by ProFI widely available to the scientific community and industrial actors by setting up a highly technical environment compatible with the production and treatment of high quality data at very high throughput and in a context of quality assurance certification.

RI Keywords
Mass spectrometry, High performance IT & bioinformatics, Oncology, Service to the community, Systems biology, Cell biology, Immunology, Plant biology, Technology survey & development, Microbiology
Classifications
RI Category
Genomic, Transcriptomic, Proteomics and Metabolomics Facilities
Scientific Domain
Information Science and Technology
Biological and Medical Sciences
Services
Proteomics

Shotgun proteomics; Targeted proteomics; Identification of post-translational modifications.

Equipment
Mass spectrometry systems

Orbitrap and Q-Trap instruments.

Collaborations
Networks
PRIME-XS
Date of last update: 24/05/2018
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